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Akinobu Hamada Selected Research

amrubicinol

2/2008Role of P-glycoprotein in accumulation and cytotoxicity of amrubicin and amrubicinol in MDR1 gene-transfected LLC-PK1 cells and human A549 lung adenocarcinoma cells.
2/2006Pharmacokinetics of amrubicin and its active metabolite amrubicinol in lung cancer patients.
2/2006Phase I and pharmacokinetic study of amrubicin, a synthetic 9-aminoanthracycline, in patients with refractory or relapsed lung cancer.

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Akinobu Hamada Research Topics

Disease

33Neoplasms (Cancer)
01/2022 - 02/2002
21Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 02/2006
12Breast Neoplasms (Breast Cancer)
04/2021 - 09/2007
7BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2014 - 06/2009
5Infections
01/2021 - 12/2004
5Lung Neoplasms (Lung Cancer)
10/2017 - 02/2006
5Acute Kidney Injury (Acute Renal Failure)
12/2011 - 04/2007
4Interstitial Lung Diseases (Interstitial Lung Disease)
03/2020 - 01/2012
4Colorectal Neoplasms (Colorectal Cancer)
06/2009 - 08/2005
4Prostatic Neoplasms (Prostate Cancer)
12/2008 - 08/2007
3Diarrhea
04/2021 - 08/2005
3Exanthema (Rash)
04/2021 - 01/2018
3Adenocarcinoma of Lung
03/2019 - 02/2008
2Anemia
04/2021 - 12/2004
2Leukopenia
04/2021 - 08/2015
2Erythema Multiforme
01/2021 - 01/2020
2Carcinoma (Carcinomatosis)
01/2021 - 06/2011
2Neoplasm Metastasis (Metastasis)
12/2020 - 06/2011
2Triple Negative Breast Neoplasms
10/2019 - 01/2019
2Brain Neoplasms (Brain Tumor)
07/2019 - 01/2015
2Body Weight (Weight, Body)
08/2016 - 12/2011
2Testicular Neoplasms (Testicular Cancer)
01/2015 - 01/2014
2Head and Neck Neoplasms (Head and Neck Cancer)
01/2015 - 01/2014
2Circadian Rhythm Sleep Disorders (Delayed Sleep Phase Syndrome)
08/2009 - 11/2005
2Subacute Sclerosing Panencephalitis (SSPE)
10/2003 - 07/2003
1Pneumonia (Pneumonitis)
10/2022
1Chronic Renal Insufficiency
01/2022
1Seizures (Absence Seizure)
11/2021
1Glioma (Gliomas)
11/2021
1Hypertension (High Blood Pressure)
04/2021
1Alopecia (Baldness)
04/2021
1Thrombocytopenia (Thrombopenia)
04/2021
1Hypoalbuminemia
04/2021
1Fatigue
04/2021
1Constipation
04/2021
1Cellulitis
04/2021
1Nausea
04/2021
1Lymphopenia (Lymphocytopenia)
04/2021
1Fever (Fevers)
04/2021
1Neutropenia
04/2021

Drug/Important Bio-Agent (IBA)

12Pharmaceutical PreparationsIBA
01/2022 - 08/2005
12Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2021 - 06/2011
7ErbB Receptors (EGF Receptor)IBA
01/2021 - 06/2011
6Imatinib Mesylate (Gleevec)FDA Link
01/2014 - 04/2008
5amrubicinIBA
01/2021 - 02/2006
5EnzymesIBA
10/2019 - 04/2011
5Peptides (Polypeptides)IBA
06/2016 - 08/2013
4Tyrosine Kinase InhibitorsIBA
01/2020 - 01/2014
4AntigensIBA
06/2016 - 08/2013
4Carboplatin (JM8)FDA LinkGeneric
07/2015 - 12/2010
4Proteins (Proteins, Gene)FDA Link
09/2013 - 02/2002
4Cisplatin (Platino)FDA LinkGeneric
12/2011 - 04/2007
4Irinotecan (Camptosar)FDA LinkGeneric
06/2009 - 08/2005
4Member 1 Subfamily B ATP Binding Cassette TransporterIBA
04/2008 - 02/2002
3Trastuzumab (Herceptin)FDA Link
01/2021 - 01/2015
3eribulinFDA Link
10/2019 - 01/2019
3Anaplastic Lymphoma KinaseIBA
03/2019 - 01/2018
3CrizotinibIBA
03/2019 - 08/2016
3GemcitabineFDA Link
04/2018 - 01/2011
3Complementary DNA (cDNA)IBA
06/2016 - 01/2014
3EpitopesIBA
06/2016 - 08/2013
3IndicanIBA
12/2011 - 04/2007
3AndrogensIBA
12/2008 - 08/2007
3amrubicinolIBA
02/2008 - 02/2006
3Ribavirin (Virazole)FDA LinkGeneric
12/2004 - 07/2003
2NivolumabIBA
01/2022 - 03/2020
2Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2020
2Alanine Transaminase (SGPT)IBA
04/2021 - 01/2019
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
04/2021 - 01/2019
2Docetaxel (Taxotere)FDA Link
04/2021 - 10/2016
2AntibodiesIBA
01/2021 - 01/2021
2Immune Checkpoint InhibitorsIBA
01/2021 - 01/2021
2TabletsIBA
10/2019 - 01/2019
2olaparibIBA
10/2019 - 01/2019
2Bevacizumab (Avastin)FDA Link
01/2019 - 12/2017
2Monoclonal AntibodiesIBA
01/2018 - 10/2017
2alectinibIBA
01/2018 - 01/2017
2Paclitaxel (Taxol)FDA LinkGeneric
06/2017 - 01/2013
2T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
01/2014 - 08/2013
2nilotinibFDA Link
01/2014 - 01/2011
2Gefitinib (Iressa)FDA Link
01/2014 - 06/2011
2CationsIBA
12/2009 - 04/2008
2Fluorouracil (Carac)FDA LinkGeneric
06/2009 - 09/2007
2ProdrugsIBA
06/2009 - 09/2007
2TegafurIBA
06/2009 - 09/2007
2VA 061 (VA061)IBA
12/2008 - 08/2007
2Testosterone (Sustanon)FDA Link
08/2008 - 06/2008
1pembrolizumabIBA
10/2022
1AfatinibIBA
01/2022
1salicylhydroxamic acid (SHAM)IBA
01/2022
1alpha-hydroxyglutarateIBA
11/2021
1Glutamic Acid (Glutamate)FDA Link
11/2021
1Guanosine Triphosphate (GTP)IBA
04/2021
1gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA
04/2021
1Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
01/2021

Therapy/Procedure

20Therapeutics
04/2021 - 07/2003
8Drug Therapy (Chemotherapy)
01/2021 - 02/2006
6Lasers (Laser)
01/2022 - 10/2017
2Molecular Targeted Therapy
01/2022 - 01/2021
2Immunotherapy
06/2016 - 01/2015